HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

James D Crapo Selected Research

Reactive Oxygen Species (Oxygen Radicals)

4/2012Manganese porphyrin, MnTE-2-PyP5+, Acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells.
7/2010Redox modulation protects islets from transplant-related injury.
6/2006Induction of antioxidant gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species.
7/2005Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity.
5/2003Preischemic and postischemic administration of AEOL10113 reduces infarct size in a rat model of myocardial ischemia and reperfusion.
3/2003Development of murine ischemic cardiomyopathy is associated with a transient inflammatory reaction and depends on reactive oxygen species.
3/2003Interaction among nitric oxide, reactive oxygen species, and antioxidants during endotoxemia-related acute renal failure.
10/2002Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


James D Crapo Research Topics

Disease

91Chronic Obstructive Pulmonary Disease (COPD)
01/2024 - 12/2002
29Emphysema
11/2023 - 07/2011
16Inflammation (Inflammations)
11/2018 - 08/2002
8Chronic Bronchitis
01/2023 - 04/2014
8Neoplasms (Cancer)
01/2017 - 03/2004
6Pneumonia (Pneumonitis)
11/2023 - 10/2002
6Ischemia
10/2023 - 10/2002
6Dyspnea (Shortness of Breath)
08/2023 - 08/2011
6Lung Injury
03/2012 - 04/2002
5Infections
10/2023 - 08/2009
5Asthma (Bronchial Asthma)
01/2023 - 08/2002
5Lung Diseases (Lung Disease)
04/2018 - 06/2003
4Disease Progression
11/2023 - 08/2016
4Hypoxia (Hypoxemia)
12/2018 - 08/2006
4Bronchopulmonary Dysplasia
10/2011 - 01/2003
3Obstructive Lung Diseases (Obstructive Lung Disease)
10/2020 - 09/2015
3Fibrosis (Cirrhosis)
01/2017 - 03/2003
3Prostatic Neoplasms (Prostate Cancer)
01/2012 - 01/2009
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
10/2009 - 10/2002
3Cardiomyopathies (Cardiomyopathy)
06/2006 - 03/2003
2Pulmonary Emphysema
11/2023 - 08/2010
2Stroke (Strokes)
10/2023 - 10/2002
2Lung Neoplasms (Lung Cancer)
01/2023 - 01/2011
2Glioma (Gliomas)
01/2016 - 02/2010
2Lymphoma (Lymphomas)
04/2012 - 07/2009
2Pulmonary Fibrosis (Fibrosing Alveolitis)
03/2012 - 04/2002
2Hemorrhage
01/2012 - 04/2003
2Neurologic Manifestations (Neurological Manifestations)
10/2009 - 10/2002
2Premature Birth (Birth, Premature)
03/2009 - 03/2005
2Myocardial Ischemia (Ischemic Heart Diseases)
05/2003 - 03/2003
2Infarction (Infarctions)
05/2003 - 10/2002
2Hyperoxia
01/2003 - 11/2002
1Airway Obstruction (Choking)
01/2024
1Hepatitis C
10/2023
1Ischemic Stroke
10/2023
1Gout
06/2023
1Genetic Risk Score
06/2023
1Chronic Disease (Chronic Diseases)
10/2020
1Atopic Dermatitis (Atopic Eczema)
07/2019
1Psoriasis (Pustulosis Palmaris et Plantaris)
07/2019

Drug/Important Bio-Agent (IBA)

37GoldIBA
11/2023 - 02/2010
26Biomarkers (Surrogate Marker)IBA
11/2023 - 04/2003
25AntioxidantsIBA
12/2016 - 05/2002
15PorphyrinsIBA
10/2023 - 10/2002
15Superoxide DismutaseIBA
01/2013 - 03/2002
12ManganeseIBA
10/2023 - 04/2003
11SmokeIBA
08/2017 - 09/2002
8Proteins (Proteins, Gene)FDA Link
01/2023 - 08/2006
8Bronchodilator Agents (Bronchodilators)IBA
11/2021 - 07/2011
8Oxygen (Dioxygen)IBA
07/2021 - 12/2002
8Reactive Oxygen Species (Oxygen Radicals)IBA
04/2012 - 10/2002
8Superoxides (Superoxide)IBA
02/2010 - 12/2002
7MetalloporphyrinsIBA
11/2021 - 10/2002
5CytokinesIBA
10/2017 - 09/2007
5EnzymesIBA
09/2008 - 05/2002
4manganese tetrakis-(N-ethyl-2 pyridyl) porphyrinIBA
11/2021 - 01/2009
4Free RadicalsIBA
08/2009 - 04/2002
4AEOL 10150IBA
04/2003 - 10/2002
3Fibrinogen (Factor I)FDA Link
06/2023 - 12/2012
3C-Reactive ProteinIBA
11/2019 - 12/2012
3Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
11/2019 - 12/2012
3GlucocorticoidsIBA
05/2015 - 07/2009
3Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2009 - 03/2003
3Oxidants (Oxidizing Agents)IBA
01/2009 - 08/2002
2Carbon MonoxideIBA
11/2023 - 07/2013
2Receptor for Advanced Glycation End ProductsIBA
11/2023 - 11/2019
2Glucose (Dextrose)FDA LinkGeneric
10/2023 - 07/2005
2Anti-Bacterial Agents (Antibiotics)IBA
11/2021 - 10/2014
2UteroglobinIBA
11/2019 - 12/2012
2ChemokinesIBA
10/2017 - 03/2003
2Interleukin-6 (Interleukin 6)IBA
10/2017 - 04/2010
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2016 - 10/2014
2CholesterolIBA
01/2016 - 03/2012
2DNA (Deoxyribonucleic Acid)IBA
08/2015 - 02/2010
2SteroidsIBA
05/2015 - 12/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2012 - 04/2010
2indium-bleomycinIBA
03/2012 - 04/2002
2Bleomycin (Blenoxane)FDA LinkGeneric
03/2012 - 04/2002
2nasIBA
02/2012 - 12/2011
2Pancreatic Elastase (Elastase)IBA
10/2011 - 08/2010
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2010 - 08/2006
2Peptides (Polypeptides)IBA
11/2007 - 01/2003
2BombesinIBA
11/2007 - 01/2003
2manganese (III) meso- tetrakis(N- ethylpyridinium- 2- yl)porphyrinIBA
02/2006 - 05/2003
1RNA (Ribonucleic Acid)IBA
10/2023
1Tissue Plasminogen Activator (Alteplase)FDA Link
10/2023
1Genetic Markers (Genetic Marker)IBA
02/2023
11-methylpyridiniumIBA
11/2021
1Gonadal Steroid Hormones (Sex Hormones)IBA
04/2020
1Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA
12/2019
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
12/2019
1Surface-Active Agents (Surfactants)IBA
11/2019
1ethylpyridiniumIBA
07/2019

Therapy/Procedure

16Therapeutics
10/2023 - 03/2003
6Radiotherapy
01/2017 - 09/2007
2Pneumonectomy (Lung Volume Reduction)
01/2018 - 01/2017
1Thrombectomy
10/2023
1Nebulizers and Vaporizers (Inhaler)
01/2023
1Orthopedic Procedures
11/2021
1Activities of Daily Living (ADL)
07/2021